About

Apoptosis is a fundamental process to regulate homeostasis of all tissues and to eliminate unwanted cells specifically in the immune system. Various parts of apoptosis signaling pathways have recently been characterized. Specifically in apoptosis pathways initiated by members of the death receptor family such as CD95 (APO-1/Fas) proteins that either contain a death domain (DD) or a death effector domain (DED) have been found to be essential.

Peter Laboratory

The Peter Laboratory is one of 15 laboratories in the Ben May Department for Cancer Research at the University of Chicago. Under the direction of Professor Marcus E. Peter, Ph.D., the laboratory investigates various aspects of the signal transduction of the apoptosis inducing death receptors with special emphasis on the CD95 receptor and the function of DED proteins.